Specification 

  Definition 

The radial arm maze is a paradigm that is often used to assess working and reference memory in rats and mice. Spatial learning and working memory could be tested using the Y maze or radial arm maze, both of which require the animal to use spatial cues to learn the location of a reward. The radial arm maze consists of a central platform surrounded by eight arms, and may be used to assess working memory. As in the Morris water maze, cues are placed around the room to distinguish the locations of the arms. During training, food rewards are placed in each arm to encourage exploration (mild food deprivation prior to training may be required to increase the rat's motivation).

citation

Postnatal MK-801 treatment of female rats impairs acquisition of working memory, but not reference memory in an eight-arm radial maze; no beneficial effects of enriched environment.(Masoumeh Nozari & Farshad Alizadeh Mansouri & Mohammad Shabani & Hojat Nozari & Nafiseh Atapour)

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